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I think the findings of NICE will be replicated in many other jurisdictions because it was balanced and sensible given the high-quality data from randomised controlled trials but also the current high price of the medication

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Further validation of these markers, particularly their specificity and sensitivity across disease stages, is needed to translate them into clinical practice

Oral weight loss treatments could help reduce hesitation in areas where needle fear is more common, while also appealing to people who are already motivated to seek treatment, but would prefer a more familiar and convenient format