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Previous studies reported that the administration of the GLP-1R agonist exendin-4 (25 nmol/kg, twice daily) inhibits learning and memory formation through the suppression of synaptic plasticity in the hippocampus of a high fat diet mouse model (Gault et al., 2010

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10.1007/s00125-013-2887-z 5

Gut microbiota mediated the individualized efficacy of temozolomide via immunomodulation in glioma