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Other combination options include metformin for insulin resistance, topiramate for appetite and food cravings, and naltrexone/bupropion for reward-driven eating patterns

But when you orally ingest a medication, the drug passes through the stomach to the small intestine, which is actually where most drugs are absorbed, she says

2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

Two-year effect of semaglutide 2.4 mg on control of eating in adults with overweight/obesity: STEP 5

However, tirzepatide does help you lose weight, and research shows that even a 5-10% weight loss can significantly reduce blood pressure, improve cholesterol levels, and lower the risk of heart disease, even in people with type 2 diabetes

Your provider will build a protocol based on your goals, your response to treatment, and your broader health picture