This medication works by mimicking the action of the naturally occurring GLP-1 hormone, enhancing glucose-dependent insulin secretion, suppressing inappropriate glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways
When researchers removed these immune cells, the mice developed less lung inflammation and scarring, suggesting macrophages play an important role in lung damage
Shop Biochem Sports Nutrition Supplements Sources mentioned in this article: Protein- and Calcium-Mediated GLP-1 Secretion: A Narrative Review
Beyond genetics, obesity itself reduces GLP-1 secretion in a harmful cycle: excess weight dampens L-cell function, lowering hormone production, which allows more overeating, which perpetuates weight gain
Combined with the reduced caloric intake many patients experience due to appetite suppression, patients may notice increased sensitivity and dryness, says Puza
Focus on nutrient-rich foods that support health and satiety