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Reduced GSH levels shown by decreases in this ratioboth in the plasma and intracellularlyreflect intracellular shifts in oxidative burden and are indicative of immune dysfunction and progression of various disease states such as infection, sepsis, and age-related immune system decline (Guerra et al., 2011

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Anti-inflammatory effects

A 12-week trial of patients receiving semaglutide demonstrated an 11.85% reduction in body weight from baseline, greater than that seen with diet and exercise alone

Nitric oxide (NO) secretion was measured using the Griess reagent

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