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Patients with CAH suffer from dehydration and vomiting, and in severe cases, the disease leads to salt wasting and even death

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Endocr Rev (1999) 20(6):876913

If your protocol calls for working concentrations in the low-micromolar range typical of cell-based assays, the stock will need serial dilution in your assay buffer

This damage is characterized by disorganization, hypertrophy, and proliferation of vascular smooth muscle cells, as well as the destruction of endothelial cells and thickening of the middle layer of the endothelium, all of which contribute to an increased risk of atherosclerosis

The ggplot2 and pheatmap R software packages were conducted to visualize the DEGs by drawing volcano plots and heatmaps, respectively