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Their dual mechanismsmicrobiota regulation and barrier enhancementinclude stimulation of beneficial bacteria such as Lactobacillus and Bifidobacterium , elevation of SCFA production (e.g., butyrate as an epithelial energy source, acetate for Treg differentiation), inhibition of TLR4/NF-B inflammatory signaling, and activation of the Nrf2/HO-1 antioxidant pathway

M., Christiansen, E., Hertz, C

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WPI) secured in the electrode pedestal (MS636, PlasticsOne) and targeted mPFC: +3.2 mm anterior and 0.8 mm lateral from Bregma, and 3.2 mm ventral to cortical surface

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Rotate sites between injections to avoid irritation