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The malignant cells expressed CD21, CD23 (subset), CD35 (small subset), CXCL13 (subset), vimentin, fascin, and clusterin, suggestive of FDC origin (Fig

PRV may also be valuable as an addition to the metabolic syndrome criteria for risk prediction at the individual level, but this needs to be confirmed by further studies

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Most human studies are crosssectional, unable to distinguish whether dysbiosis drives CKD progression or merely reflects the uremic milieu