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232 During breast cancer progression, the stiffened fibrotic tumor microenvironment enhances the TGF autocrine pathway in tumor-associated macrophages (TAMs), activating their collagen biosynthesis program

Rice DC, Lee JH, Jimenez C, Eapen G, Stewart J, Hofstetter WL, Mehran R, Vaporciyan AA, Walsh GL, Swisher , SG

Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects

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The heart rate was considerably lower at 3 and 4 min, indicating improved cardiovascular efficiency