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This creates a feeling of fullness, or satiety , which reduces appetite and food intake

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Moving straight to 18:6 or OMAD in the first weeks of GLP-1 therapy is a common mistake

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The proglucagon gene encodes a 180-amino acid precursor that, depending on the tissue-specific expression of processing enzymes, yields different active peptides: in the pancreatic alpha cells, PCSK2 processing produces glucagon