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This effect is supported by increased glucose flux through the noncanonical PPP, resulting in higher NADPH production, which promotes lysosomal maturation and maintains intracellular redox balance, thereby facilitating more efficient clearance of ACs [92] (Fig

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Modulation of amyloid precursor protein cleavage by cellular sphingolipids

HPN-07, a free radical spin trapping agent, protects against functional, cellular and electrophysiological changes in the cochlea induced by acute acoustic trauma

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For panel a-b , n = 5 mice for V and R, n = 7 mice for P and P+R