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Accessed 11 Jan 2022 Grant CM, Dawes IW (1996) Synthesis and role of glutathione in protection against oxidative stress in yeast

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Hil.) on pentylenetetrazol-induced seizures in Wistar rats

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Thus, while IN chelation is promising for directly targeting the brain and CNS, it still requires careful consideration of formulation strategies (e.g., nanoparticle targeting or controlled-release systems) to improve site specificity, especially for drugs with a narrow therapeutic window

Interestingly, only a few studies have examined the role of GPx1 in modulating mitochondrial ROS production