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In zinc deficient rats, kidney functions are compromised due to structural abnormalities, including reduced number of nephrons and renal fibrosis, and functional impairments, such as reduced glomerular filtration rate and proteinuria [458]
Adding the positive control, digitonin, resulted in a large increase in cytotoxic signal
Similarly, MIA can be modeled in rodents using the toll-like receptor 3 agonist polyriboinosinic-polyribocytidilic acid poly(I:C), which leads to autism-like behavior in offspring (Fujita et al., 2020)
De Boni M
For purposes of this part, the terms in this part have the same meanings as 42 CFR 512.110 and 414.1300 unless otherwise stated
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