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Journal of Neuropathology and Experimental Neurology 69(9):918929

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Additionally, reactive oxygen species (ROS), secreted in large amounts by activated microglia, can activate the Rho-kinase pathway, leading to pericyte contraction and inhibition of vasodilation, thus promoting vasoconstriction (Hartmann et al., 2021)

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Sun 2021, PMID 34827486 a clean, independent APP/PS1 Alzheimer's-model mouse study)