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Phentermine increases heart rate by 515 beats per minute and systolic blood pressure by 210 mmHg

Bloating typically eases as your body adjusts to the maintenance dose, which often happens after about 20 weeks

Adjust as you go

Last year removing Zepbound from the formulary forced thousands of patients to consider whether they wanted to stop taking weight loss medicine or switch to Wegovy, an injectable drug that uses a different compound

Chen D, Zhang T, Lee TH (2020) Cellular mechanisms of melatonin: Insight from neurodegenerative diseases

These effects indicate the medication is working, not that something is wrong