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As summarized earlier, ferroptosis arises from a dysregulated balance between pro-ferroptotic cues (e.g., labile iron accumulation and PUFA enrichment) and protective mechanisms, including the SLC7A11GSHGPX4 axis, GCH1BH4 pathway, FSP1CoQH2 system, DHODHCoQH2 cascade, and MBOAT1/2-mediated monounsaturated fatty acid (MUFA) synthesis (280282)

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At 48 weeks, the least-squares mean percentage change in the retatrutide groups was -8.7% in the 1-mg group, -17.1% in the combined 4-mg group, -22.8% in the combined 8-mg group, and -24.2% in the 12-mg group, as compared with -2.1% in the placebo group

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Aguacate: Esta fruta es una fuente vegetal notable de L-Carnitina, aunque menos concentrada que en las fuentes animales