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The answer depends on which indication is being considered

Real-world observations suggest that properly dosed sublingual semaglutide at therapeutic levels can produce meaningful weight loss, typically in the range of 8% to 15% body weight over 12 to 16 weeks

In gastrointestinal inflammatory conditions , observational data suggest that GLP-1RA use in patients with inflammatory bowel disease is associated with a lower risk of IBD-related surgery in both ulcerative colitis and Crohns disease, and early studies have explored whether GLP-1RA injections can reduce pain in irritable bowel syndrome patients (the answer was yes)

While the drugs active ingredients might not cause fatigue directly, the way Mounjaro alters the bodys digestion and metabolism can lead to significant physical exhaustion

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This test is the predominant way physicians assess overall kidney function, as well as check for and monitor CKD