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In this preclinical study, we investigated how alcohol, fluoxetine, and their combination affect the gut microbiota, intestinal barrier integrity, peripheral inflammatory markers, and neuroimmune signaling

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Advanced fibrosis was defined as presence of histologic fibrosis stage F3

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Holst suspects this may help explain how GLP-1 agonists influence organs that lack direct receptor expression, including parts of the central nervous system

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