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However, there are established patterns based on clinical observations

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While the study did not directly measure fat loss, elevated GH is well known to promote fat breakdown (lipolysis), providing a biological rationale for weight-loss claims

Furthermore, ApoE4 + carriers display higher fertility rates in areas of high pathogen exposure (van Exel et al., 2017), suggesting an evolutionary adaptation against a variety of pathogens that would be selected for in our evolutionary past as ApoE4 is considered the original ancestral phenotype (Fullerton et al., 2000)

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