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However, concerns are emerging related to the potential loss of muscle mass linked to these treatments, with significant implications for long-term health, as came out of a recent editorial in the prestigious journal The Lancet entitled Muscle matters: the effects of medically induced weight loss on skeletal muscle, which underlined how GLP-1 receptor agonists have revolutionized the treatment of obesity and proven to be effective in reducing body weight

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The severity of malnutrition, nutrient deficiencies, and muscle loss is unknown for healthy populations

doi: 10.1016/j.biocel.2004.11.009