what organ produces glutathione system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Glutathione - PMC

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In such systems, the ascorbateglutathione cycle, together with TRXs, PRXs, glutaredoxins (GRXs), and antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT), ensures appropriate redox-mediated regulation, so that ROS, ascorbate, and glutathione can accumulate in the required compartment-specific manner

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