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Persistent lipohypertrophy may require referral to a diabetes specialist nurse or dermatologist for further evaluation, though surgical intervention is rarely necessary

There is no established link between standard B12 supplementation and serious adverse events in healthy individuals

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All of these changes make the skin more susceptible to damage and slower to heal

(2010) Selenium, but not lycopene or vitamin E, decreases growth of transplantable dunning R3327-H rat prostate tumors