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In animal models, intra-articular administration of liraglutide reduced the secretion of inflammatory cytokines such as IL-6, the expression of inflammatory genes in chondrocytes, the amount of proinflammatory M1 macrophages, and improved pain-related behaviors 104

The mentioned potential benefits hold true in general for any transdermal delivery system and not GLP- patches specifically, as these still lack real-world evidence

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