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Cisplatin treatment upregulated the expression of P66Shc in vivo and in vitro and promoted its mitochondrial translocation to exacerbate ferroptotic cell death and induce cisplatin-induced AKI [173]

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Conjugated Linoleic Acid (CLA):A naturally occurring fatty acid that has been shown to help reduce body fat and increase lean muscle mass

Excessive hair shedding beyond the normal 50-100 strands daily may signal omega 3 deficiency affecting follicle health

In another study, prepartum L-carnitine administration in sheep decreased serum NEFA concentrations without altering HBA, triglyceride, or glucose levels (Pancarc et al., 2007)

However, no increased risk of perianal or stricturing complications has been observed in CD patients (86, 87)