When combining these medications, be alert for: Excessive nausea or gastrointestinal distress that affects daily functioning or medication adherence Significant mood changes, increased anxiety, agitation, or symptoms of mania Unusual fatigue or changes in sleep patterns Signs of dehydration, particularly if experiencing vomiting or diarrhoea Contraindications and Cautions: Wegovy is contraindicated in pregnancy and should be discontinued at least 2 months before a planned pregnancy due to its long half-life
Another clinical trial, published in Diabetes, Obesity & Metabolism , found that people taking semaglutide were more likely to experience bloating and indigestion compared to those taking a placebo
Compared with placebo, significantly higher proportions of patients with cilofexor/firsocostat had a reduction in NAS 2 points
This small percentage provides adequate amounts when the dose is sufficiently high
Most of these were accidental overdoses, where people mistakenly took two doses or took the wrong dose
World Obesity Federation
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