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Diabetes Care 40 , 12261232 (2017)
The other GLP-1RAs included lixisenatide, liraglutide, exenatide, dulaglutide, and albiglutide
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After matching for age, sex and comorbidities, the researchers found the benefits of GLP-1RAs were clear and consistent across all sensitivity analyses, using propensity score matching to control for potential confounders
Who Should and Should Not Consider GLP-1 Therapy With Crohn's Disease Candidates for GLP-1 therapy with Crohn's disease typically have well-controlled or remission-stage disease, stable inflammatory markers, adequate nutritional status, and documented need for weight management
That structural damage reduces receptor binding affinity, so the medication may not activate GLP-1 receptors effectively even though the labeled dose is unchanged
