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Peters DE,Tallon C,Pandey R,Thomas AG,Dash RP,Seiwert T,Majer P,Leone RD,Powell JD,Slusher BS

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When cellular glutathione levels drop, the accumulation of unneutralized reactive oxygen species provokes mast cells to become hyper-reactive, inappropriately releasing massive quantities of histamine into the bloodstream

Serum concentrations of n-3 PUFAs have shown an inverse association with both the extent of skin lesions and the PASI scores in patients (38)