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RESULTS FOXO4 is specifically expressed in Leydig cells within human testes To evaluate the pattern of FOXO4 expression, tissue sections of human testes were immunofluorescently stained and then photographed using confocal microscopy

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References: Kim et al

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Furthermore, important questions remain, including the long-term durability of weight loss and its maintenance after treatment discontinuation, as well as its impact on major cardiovascular outcomes

Those results, expected in 2026, will likely confirm and potentially extend the Phase 2 findings given the consistency of dose-response data