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Another study that used etomoxir showed that inhibition of CPT I activity by 50% specifically in the liver led to an enlarged liver in a murine model [61]

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Novo Nordisk (NOV: N) today released promising late-stage trial results for its CagriSema - a fixed-dose combination of semaglutide and the amylin analogue cagrilintide obesity treatment, as the Danish pharmaceutical giant seeks a next-generation alternative to its blockbuster Wegovy (semaglutide) weight-loss drug