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Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)
Currently, intranasal delivery is suggested as a promising alternative to invasive strategies because it can directly transport the molecules to the brain bypassing the BBB (Crowe et al., 2018
Mounjaro (tirzepatide) prescribing information
10.1038/s41556-022-00949-1 13 ClaraA.MartaK.PaulaM.-S.Lpez-PoloV.TorresT.PuigS.et al (2024)
Immediate medical attention is necessary to prevent life-threatening complications associated with alcohol poisoning
Vascular smooth muscle cells specific deletion of angiopoietin-like protein 8 prevents angiotensin II-promoted hypertension and cardiovascular hypertrophy
