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n = 8, with 6 patients receiving setmelanotide and 2 assigned to placebo)

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Citing these recent works will both address the reviewers concern about currency and strengthen the argument that GSH-responsive strategies are maturing toward precision, clinically relevant theranostics [20]

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Growth hormone is often said to have anti-insulin activity, because it supresses the abilities of insulin to stimulate uptake of glucose in peripheral tissues and enhance glucose synthesis in the liver

This selectivity profile is why Ipamorelin replaced first-generation GHRPs as the preferred ghrelin-receptor agonist in clinical practice