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85 Pro-inflammatory and pro-fibrotic disc / bone marrow cross-talk has also been demonstrated in patients with Modic changes

Reactive oxygen species can provide atheroprotection via NOX4-dependent inhibition of inflammation and vascular remodeling

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Sarchielli P, Zaffaroni M, Floridi A et al (2007) Production of brain-derived neurotrophic factor by mononuclear cells of patients with multiple sclerosis treated with glatiramer acetate, interferon- 1a, and high doses of immunoglobulins