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It may represent a significant step forward in pharmaceutical development

Moreover, bone health might be affected in the long term, with a potential decrease in bone mineral density and increased fracture risk, highlighting the need for calcium and vitamin D supplementation to maintain skeletal health

Nature 528 , 262266 (2015)

however, myo-inositol and DCI appear to have different effects on ovarian and pituitary hormone production, and the optimal ratio of myo-inositol to DCI for treatment of PCOS remains unresolved