There is much to like, including the RCT design
For instance, platelet-derived growth factor (PDGF) facilitates neuronal growth and differentiation, orchestrates the interactions between neurons and glial cells, and has the potential to mitigate excitotoxicity [142]
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They may be considered as part of dual or triple therapy when specific criteria are met, including BMI thresholds (35 kg/m or 32.5 kg/m in certain ethnic groups) and when weight loss would benefit other obesity-related comorbidities
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Derin, N., Agac, A., Bayram, Z., Asar, M