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Thornton J, Edwards R, Mitchell P, Harrison RA, Buchan I, Kelly SP

Third-Party Testing: High-trust brands will always test their batches for purity and potency through independent labs

Database 2024:113

After exposure to an irritant, the irritant will exert toxic effects on keratinocytes

At the same time, you lose electrolytes like sodium and potassium, which help nerve cells communicate effectively

Where adverse events are discovered to be related to the mechanism of action of the drug or therapy at this late stage, perhaps through meta-study of clinical trials and amongst particular sub-sets of the population, they are often over-estimated due to the regression to the mean effect, i.e., in large sample sizes, random noise contributes to data points between the mean and the most extreme example, making the most extreme example appear to be a random overestimate of the true effect