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Oxidative stress exacerbates A toxicity, promotes tau phosphorylation, and impairs mitochondrial function, further accelerating neuronal degeneration (Butterfield and Halliwell 2019)
A 1:1 ratio is scientifically optimal. No clinically validated ratio was identified
The formulation is prepared by adding the target weight percentage of a JNK inhibitor that has been micronized and gamma irradiated to the appropriate amount of medium chain triglyceride that has been sterilized via filtration
This is why formulation design matters so much
The evidence is limited and frequently from small studies
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