The electrophysiology and cardiac function of these patients are entirely normal under baseline conditions (16)
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Non-alcoholic steatohepatitis (NASH) , characterised by inflammation and hepatocyte injury, or advanced fibrosis and cirrhosis can disrupt normal liver function
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Mix protocols can reveal combined effects where the combined response exceeds the sum of personal effects, antagonistic interactions where one peptide tunes anothers effects, or paired mechanisms where different peptides affect distinct but related processes
Nature Cell Biology , 20 (4), 373381