The importance of these findings relates to the fact that in the pre-initiation and/or early stages of colon carcinogenesis the disruption of cellular defence mechanisms (consisting of a battery of detoxifying or antioxidant enzymes) would make cells more susceptible to DNA damage by both unwanted by-products of normal cellular metabolism (Fig
J Gastroenterol Hepatol 30:657666 Viasus D, Ramos O, Ramos L, Simonetti AF, Carratal J (2017) Solithromycin for the treatment of community-acquired bacterial pneumonia
A., Hansen, M., Kristiansen, J., Nabe-Nielsen, K
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Health 11 , 119 (2011)
