Its a drug given to type 2 diabetics to lower their blood glucose levels, but its gotten quite popular among the biohacking scene More specifically, it decreases the production of glucose in the liver, decreases glucose uptake in the gut, and increases overall glucose utilization by improving insulin sensitivity in skeletal muscle Rhonda, personally, has never taken it Many claim metformin supplementation improves lifespan, but Findings have been skeptical in rodent models, with many variations among dose, gender, and dose timing (specifically, the age of the mouse when given the first treatment) Certain combinations of the above actually decrease lifespan, particularly in male mice Indeed, among type 2 diabetics, taking metformin improves lifespan, but if youre healthy, think twice Doesnt metformin reduce the risk of cancer

Its active ingredient, curcumin, has a broad spectrum of pharmacological activities, with anti-inflammatory, hypoglycaemic, antioxidant, healing and antimicrobial properties
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53 Low B 12 concentrations in the body may be present in different pathophysiological situations, including pregnancy, old age, smoking, and comorbidities such as hypertension, diabetes mellitus, pancreatic insufficiency, autoimmune gastritis, gastrectomy or gastric bypass, diseases or resection of the ileum, bacterial overgrowth, celiac disease, inflammatory bowel disease, or uremia-related malnutrition
[DOI] [PubMed] [Google Scholar] Jomova K, Makova M, Alomar SY, Alwasel SH, Nepovimova E, Kuca K, Rhodes CJ, Valko M
Long-term effects beyond 8-12 week cycles remain unknown due to the nature of available evidence