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( c ) Mean fiber photometry bulk calcium fluorescence (z-score) from elPBN VehTRAP neurons (n = 6 male mice) in response to SQ saline (gray) or SQ semaglutide (blue
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The overall distribution of selection preferences was as follows: the first-choice therapy: 17.2%, the second-choice therapy: 27.8%, the third-choice therapy: 32.0%, the fourth-choice therapy: 18.3%, and the fifth-choice therapy: 4.7%
The weight loss curve had not plateaued at 48 weeks, meaning longer treatment could produce even greater reductions
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