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Human data is scarce to nonexistent, according to The Times

And Ive personally known numerous vegans who neglected B12 and subsequently experienced fatigue and temporary neuropathy that resolved upon supplementation

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For mild conditions: 1 injection 2-3 times a week

Typical trial exclusion criteria for retatrutide studies, consistent with those applied to similar investigational and licensed medicines in this class, have included: pregnancy or breastfeeding (with active contraception requirements during participation)