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Older patients or those with multiple comorbidities may experience slower improvement

Secondary clinical outcomes Japanese Orthopaedic Association (JOA) and Oswestry Disability Index (ODI) scores were used to assess improvements in lumbar spine function, with higher JOA scores indicating better function and lower ODI scores indicating improvement

Goal: Support metabolic efficiency through NNMT inhibition, potentially enhancing fat oxidation and NAD+ levels [1] [2]

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