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The loading dose regimen achieved the quickest and highest increase, reaching a median vitamin B12 concentration of 1090 pmol/L (reference range 350-650 pmol/L) after 14 days

In mitochondria [edit] The metabolism of propionyl-CoA occurs in the mitochondria and requires Vitamin B 12 (as adenosylcobalamin) to make succinyl-CoA

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