no more semaglutide New Report Showing Weight Loss Drugs Are Not a Long-Term Solution Is Surprise, Doctors Say FDA ends semaglutide shortage, closing

But her first go-around with the medication didnt quite stick

doi: 10.1186/s12916-021-02204-0 [DOI] [PMC free article] [PubMed] [Google Scholar] 24.Kim DD, Wang L, Lauren BN, et al

In general, no therapeutic intervention is required

TRIUMPH-1 trajectory (80 weeks + extension): Week 80: 28.3% average weight loss (2,339 patients) 104-week extension (BMI 35 subgroup): 30.3% average weight loss Weight loss does not plateau at 80 weeks it continues in longer treatment The TRIUMPH-1 104-week extension is the most important long-term efficacy signal we have

Read that number again

Specifically, in animal models of atherosclerosis, namely, ApoE / and LDL receptor / knockout mice, GLP1 treatment reduced plaque size (Bjrnholm et al., 2020)