Over time, pharmacological engineering enabled: Short-acting injectables (e.g., exenatide) Long-acting once-weekly injectables (liraglutide, semaglutide) Multi-target incretin therapies (tirzepatide) Oral peptide formulations and now oral small molecules The most recent breakthrough is the development of orally available GLP-1 receptor agonists, including: Orforglipron (Lilly) Elecoglipron (AstraZeneca) These compounds eliminate the need for injection and could dramatically expand accessibility and adherence in obesity and diabetes populations
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This causes the fat cells to shrink, and you lose weight
Final results, once swelling fully resolves, can take several months to appear, depending on the procedures performed
With the percentage of patients undergoing efforts at weight loss who are likely to be successful, there is a significant likelihood of increased business for a company like InMode (INMD) which sells products used to improve muscle tone after abdominoplasty or Establishment Labs (ESTA)
For patients who prefer not to use injections or have difficulty with self-injection, this may be an alternative delivery option when prescribed