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reported that this effect diminished over time, becoming less pronounced after one year of treatment

Int J Mol Med 43(4):17581768 Zhang A, Wang H, Qin X, Pang S, Yan B (2012) Genetic analysis of SIRT1 gene promoter in sporadic Parkinsons disease

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Discuss common gastrointestinal side effects and strategies to minimise (eat slowly, smaller portions)