Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity
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Functioning as a potent exercise mimetic, this small-molecule compound enhances mitochondrial function, fatty acid oxidation, and oxidative muscle fiber composition, thereby improving exercise endurance, cardiac metabolic efficiency, and systemic energy expenditure without increasing food intake 1-4 .
Animal research has confirmed the high oral bioavailability of 5-amino-1MQ, making it suitable for administration in capsule form [14]