doi: 10.1016/j.physbeh.2022.113967 Summary Keywords glucagon-like peptide-1 receptor agonists, psychiatric adverse events, disproportionality analyses, FAERS database, pharmacovigilance study Citation Chen W, Cai P, Zou W and Fu Z (2024) Psychiatric adverse events associated with GLP-1 receptor agonists: a real-world pharmacovigilance study based on the FDA Adverse Event Reporting System database
Las fibras solubles fermentables, presentes en alimentos como: Avena y cebada (ricas en beta-glucanos) Legumbres (frijoles, lentejas, garbanzos) Alcachofas y esprragos (fuentes de inulina) Semillas de cha y linaza Manzanas y peras con cscara Estas fibras son fermentadas por bacterias intestinales beneficiosas, produciendo cidos grasos de cadena corta que pueden estimular las clulas L secretoras de GLP-1, segn estudios principalmente en modelos experimentales
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Archie SR, Al Shoyaib A, Cucullo L
Key Takeaways Side effects are predictable, dose-dependent, and time-limited for most patients Nausea typically peaks within 48 weeks and improves with body adaptation Each dose escalation produces a temporary, milder return of symptoms Weeks 26 are when most patients quit this is the wrong time to stop Protein, hydration, and resistance training prevent the most common long-term issues (muscle loss, fatigue, constipation) Serious side effects are uncommon but recognisable knowing the warning signs matters If symptoms are unmanageable, ask your prescriber to delay (not skip) a dose escalation References Hawkins-Jarrett ZC, PharmD
Cardiovascular Diseases: By improving metabolic health, Semaglutide can reduce the risk of heart-related issues
