B12 deficiency has been linked to depression, memory loss, and cognitive decline
GLP-1 stands for Glucagon-Like Peptide-1, which is a hormone in the body that is involved in blood sugar regulation and appetite control
Furthermore, SIRT3 directly deacetylates and activates carnitine palmitoyltransferase 2 (CPT2), an obligate step in mitochondrial long-chain FAO, to enhance the LC turnover pool in adipocytes, which in turn promoted lipid metabolism and anti-inflammatory polarization in macrophages
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GLP-1 and analogs increase glucose consumption in mature cells whereas they reduce it in progenitor cells and ADSCs, which can lead to decreased production of ATP and energy deficiency
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