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Figure 3 3.1 Inhibition of oxidative stress An imbalance between pro-oxidants and antioxidants can result in tissue and organ damage, known as oxidative stress. This imbalance may arise from excessive production of ROS or deficiencies in the antioxidant defence mechanisms (14)

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138 Therefore, the activation of ferroptosis seems to be an important goal in cancer therapy, and triggering NFS1 might be a suitable strategy

[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Sun Q., Li G., Zhao F., Dong M., Xie W., Liu Q., Yang W., Cui R

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